Interleukin 2 Mutant Protein for Regulating T Cell Transmission

摘要

The present invention relates to IL-2 mutant protein and IL-2 mutant FC fusion molecule, which are preferred to transmit and activate regulatory T cells and can be mass-produced. The invention also relates to Molec variants.Although N 297 has no glycosylation, it lacks or significantly reduces the effective function and high stability of human Igg1 FC ULS. The present invention also relates to glycosylated Liers peptides expressed in mammalian cells.