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Method for treating multicentric breast cancer

机译:治疗多中心乳腺癌的方法

摘要

The invention relates to medicine, in particular to oncology and can be used for treating multicentric breast cancer.Summary of the invention lies in the fact that are carried out three courses of polychemotherapy with an interval of 28 days, namely Cyclophosphamide 600 mg/m2, Doxorubicin 30 mg/m2 and 5-Fluorouracil 500 mg/m2, which is administered on the 1st and 8th day, then a 0.005% Imunofan solution 1 ml is administered intramuscularly, for 5 days, after 21 days is carried out the radiation therapy with a total dose of 44 Gy, 2 Gy per session, then a 0.005% Imunofan solution 1 ml is repeatedly administered intramuscularly, prior to surgical intervention is taken 200 ml of blood from the patient and centrifuged, afterwards in one recipient is stirred 10 ml of plasma and 10 mg of Methotrexate, and in another recipient is stirred 10 ml of plasma, 10 ml of a mixture of formed elements and 30 mg of Doxorubicin, then the mixtures are incubated at 37°C, for 40 min, during the surgical intervention using methylene blue solution are isolated the lymphatic ducts, then the mixtures from the first recipient are introduced into one of the lymphatic ducts of a large caliber in the proximal direction of the vessel, after which the duct is ligated and incised, radical mastectomy is performed to remove level I, II and III lymph nodes, and tissues adjacent to the removed organ are infiltrated with the mixture from the second recipient.
机译:本发明涉及医学,特别是涉及肿瘤学并且可用于治疗多中心乳腺癌。本发明的概述在于以下事实:以三个疗程进行多化学疗法,间隔为28天,即环磷酰胺600 mg / m2,在第1天和第8天给药阿霉素30 mg / m2和5-氟尿嘧啶500 mg / m2,然后经21天的放射治疗后,肌肉内给药0.005 Immunofan溶液1 ml,持续5天。总剂量为44 Gy,每次疗程2 Gy,然后肌肉内反复施用0.005%的Imunofan溶液1 ml,然后从患者中取出200 ml血液进行离心分离,然后在一位接受者中搅拌10 ml血浆和10 mg甲氨蝶呤,然后在另一个接受者中,将10 ml血浆,10 ml所形成元素的混合物和30 mg阿霉素混合,然后在手术过程中于37°C孵育40分钟使用亚甲蓝溶液进行的分离术将淋巴管分离,然后将第一个接受者的混合物沿血管近端方向引入大口径的淋巴管中,然后结扎并切开该管,行根治性乳房切除术为了去除I,II和III级淋巴结,将来自第二接受者的混合物浸润到与去除的器官相邻的组织。

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