TETRAHYDROPYRIMIDODIAZEPINE AND TETRAHYDROPYRIDODIAZEPINE COMPOUNDS FOR TREATING PAIN AND PAIN RELATED CONDITIONS.

摘要

The present invention relates to new compounds of general formula (I) that show great affinity and activity towards the subunit a2d of voltage-gated calcium channels (VGCC), especially a2d-1 subunit of voltage-gated calcium channels or dual activity towards subunit a2d of voltage-gated calcium channels (VGCC), especially a2d-1 subunit of voltage-gated calcium channels, and noradrenaline transporter (NET). The invention is also related to the process for the preparation of said compounds as well as to compositions comprising them, and to their use as medicaments. (I).