T-lymphocyte and T-lymphocyte receptor for immunococcal cancer

摘要

This note refers to T lymphocyte (TCR) receptors attached to tumor antigens, which can specifically identify carcinogenic cells, T lymphocytes expressing cancer cells, methods of producing these cells and methods of handling these tumors. Specifically, this note refers to several TCR and their variants, which bind to one or two HLA molecules and attach a cucumber, such as igf2bp3-001 (SEQ ID n: 1), which contains the amino acid sequence of kiqeiltqv. In addition, this description also refers to cucumber and protein,Nucleic acids and cells are used in immunotherapy. In particular, this note refers to cancer immunotherapy. In addition, this description also refers to the cortitis of T lymphocytes associated with tumor, alone or in combination with other tumor related cucumbers, which can be used as the principle of active pharmacology in vaccine ingredients to stimulate anti-tumor immune response or stimulate immune response. Pre lymphocyte T, they will be transferred to the patient. Cucumbers are bound to molecules of the maximum histocompatibility (MHC) complex,Or cucumbers themselves, or antibody targets, soluble receptors of lymphocytes, and other combined molecules