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2.4. New anti carcinogens replace 2.4

机译:2.4。新的抗致癌物取代2.4

摘要

It refers to a compound of formula I, wherein R1 can be a 5-8 member ring shaped, a mixed heterosexual composed of 8-13 atoms, including 1, 2, 3 and 4 heteromorphisms selected from O, N and S; LW can be an asphalt (C1-C10),A linear or branched asphalt (C1-C10), a cyclopentanediol (C3-C10),R2 may be nr5r6, among which R5 and R6 may be hydrogen, an alternative C1-C10 tar, an alternative c13-c10 halide; R3 may be h, halogen, C1-C10 linear tar; m may be 1, 2 or 3; W may be 0 or 1. The most popular compound is 2 - (4-chlorobenzene) - 4 - (4-tert-butilaminopperidin-1-il) - quinolina (2.2);2 - [3-methyl-4 - (pirimidin-2-ilamino) phenyl amide] - 4 - (4-tert-butilaminoperidin-1-il) - quinine (3.4). He also mentioned a combination of pharmacology composers. This ingredient can inhibit the growth or differentiation of carcinogenic mother cells and is useful in the treatment of cancer.
机译:它是指式I的化合物,其中R 1可以是5-8元环状,由8-13个原子组成的混合异性,包括1、2、3和4个选自O,N和S的异质性; LW可以是沥青(C1-C10),线性或支链沥青(C1-C10),环戊二醇(C3-C10),R2可以是nr5r6,其中R5和R6可以是氢,也可以是C1-C10焦油,替代的c13-c10卤化物; R3可以是h,卤素,C1-C10线性焦油; m可以是1、2或3; W可以是0或1。最受欢迎的化合物是2-(4-氯苯)-4-(4-叔-butilaminopperidin-1-il)-喹啉(2.2); 2- [3-甲基-4-(嘧啶[-2-ilamino)苯基酰胺]-4-(4-叔-butilaminoperidin-1-il)-奎宁(3.4)。他还提到了药理学作曲家的组合。该成分可抑制致癌母细胞的生长或分化,可用于治疗癌症。

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