1-alkylquinine indolyl acetates, method for obtaining them and application as bacteriostatic and bactericidal agents

摘要

the subject application is indolilooctany 1 - alkilochininy of general formula 1, where r is an alkyl substituent length from 1 to 18 carbon atoms.the application also includes how to receive new indolilooctanów 1 - alkilochininy referred to, which is that bromide 1 - alkilochininy of general formula 2.where r means alkyl substituent length from 1 to 18 carbon atoms, is dissolved in methanol or ethanol or propan-2-ol and subjected to chemical reaction with potassium hydroxide.or with sodium hydroxide or lithium hydroxide in a mole ratio of 1: 1, in 20°c temperature and time at least 30 minutes, then odsącza to wytrąconą inorganic salt.and to filtrate the following acid indolilooctowego model 3 in a mole ratio of 1: 1, after which the mixed system in time from 15 to 30 minutes, preferably 20 minutes,maintaining a constant temperature system of 20°c, subsequently with the removed solvent, and the residue is dried under reduced pressure, preferably at 30 oc.the application concerns also apply indolilooctanów 1 - alkilochininy of general formula 1,where r means alkyl substituent length from 1 to 18 carbon atoms as bacteriostatic and bactericidal.