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FRAGMENTS OF UNACYLATED GHRELIN FOR USE IN THE TREATMENT OF PRADER-WILLI SYNDROME
FRAGMENTS OF UNACYLATED GHRELIN FOR USE IN THE TREATMENT OF PRADER-WILLI SYNDROME
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机译:未酰化的生长素释放肽片段用于治疗普拉德-威利综合症
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摘要
A method and a composition for decreasing ghrelin levels and/or decreasing ghrelin/unacylated ghrelin ratio in a subject, the method comprising administering an effective amount of unacylated ghrelin, a fragment thereof, an analog thereof and/or pharmaceutically acceptable salts thereof to the subject wherein a reduction in ghrelin levels and/or a reduction in ghrelin/unacylated ghrelin ratio is beneficial to the subject. Also, use of ghrelin level and/or ghrelin/unacylated ghrelin ratio as biomarkers for determining a subject's likelihood of responding to and/or benefiting from administration of unacylated ghrelin.
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