首页> 外国专利> A PROCESS FOR THE PRODUCTION OF OF 19-NORPREGN-4-EN-3,20-DIONE-17.ALPHA.-OL (GESTONORONE) AND INTERMEDIATES THEREFOR

A PROCESS FOR THE PRODUCTION OF OF 19-NORPREGN-4-EN-3,20-DIONE-17.ALPHA.-OL (GESTONORONE) AND INTERMEDIATES THEREFOR

机译:19-NORPREGN-4-EN-3,20-DIONE-17.α-OL(羟色酮)的生产及其中间体的制备方法

摘要

The present invention relates to a new stereoselective process for the synthesis of 17(()-17-aceryl-17-hydroxy-estr-4-en-3-one of formula (I), as well as to the new intermediates of the process. The 17(()-17-acetyl-17-hy droxy-estr-4-en-3-one (gestonorone) is an important intermediate in the synthesis of the active ingredients having progestogen activity-such as gestonorone capronate and nomegestroi acetate. Formulas (I), (II) and (III).
机译:本发明涉及合成式(I)的17(()-17-丙烯酰基-17-羟基-estr-4-en-3-one)的新的立体选择方法,以及该化合物的新中间体。 17(()-17-乙酰基-17-hy droxy-estr-4-en-3-one(孕酮)是合成具有孕激素活性的活性成分的重要中间体,如己酸孕酮酮和去甲孕烯式(I),(II)和(III)。

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