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AN ORAL PHARMACEUTICAL FORMULATION COMPRISING SUSTAINED-RELEASE GRANULES CONTAINING TAMSULOSIN HYDROCHLORIDE

机译:包含盐酸taulsulosin的缓释颗粒的口服药物制剂

摘要

An oral pharmaceutical formulation containing sustained-release granules including tamsulosin hydrochloride and a method of preparing the oral pharmaceutical formulation are provided. In the oral pharmaceutical formulation, the sustained-release granules includes about 10 parts to about 300 parts by weight of polyvinyl acetate, about 5 parts to about 250 parts by weight of hydroxypropyl methylcellulose, and about 1 part to about 450 parts by weight of a diluting agent with respect to 1 part by weight of tamsulosin hydrochloride, and a weight ratio of the sustained-release granules with respect to 1 part by weight of tamsulosin hydrochloride is about 360 to 495 parts by weight.
机译:提供了包含持续释放的颗粒的口服药物制剂,所述缓释颗粒包括盐酸坦索罗辛,以及制备该口服药物制剂的方法。在口服药物制剂中,缓释颗粒包含约10重量份至约300重量份的聚乙酸乙烯酯,约5重量份至约250重量份的羟丙基甲基纤维素和约1重量份至约450重量份的α-淀粉。相对于1重量份的盐酸坦洛新,稀释剂和缓释颗粒相对于1重量份的盐酸坦洛新的重量比为约360至495重量份。

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