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METHOD OF QUANTITATIVE MEASUREMENT OF PARTICLE CONTENT USING HYDRATED STATE IMAGINGMETHOD OF QUANTITATIVE MEASUREMENT OF PARTICLE CONTENT USING HYDRATED STATE IMAGING
METHOD OF QUANTITATIVE MEASUREMENT OF PARTICLE CONTENT USING HYDRATED STATE IMAGINGMETHOD OF QUANTITATIVE MEASUREMENT OF PARTICLE CONTENT USING HYDRATED STATE IMAGING
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机译:利用水合态成像定量测量粒子含量的方法一种利用水合态成像定量测量粒子含量的方法
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摘要
The method is for quantitative measurement of particle content using hydrated state imaging such as CryoTEM. A sample of virus-like particles (VLPs) or virus particles is provided. Preferably, the sample is rapidly frozen into a cryogenic liquid at a cryogenic temperature. While at the cryogenic temperature, the particle content of each VLP in the frozen sample is observed in the CryoTEM. An amount of the particle content of the VLPs is determined to assess whether the VLPs are empty or not.
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