COMPOSITION OF AN ANTIBACTERIAL CREAM WITH AQUEOUS EXTRACT OF KARIMBUAYA (Euphorbia neriifolia), PAKO (Diplazium esculentum) AND MAYANA (Coleus blumei) FOR SKIN INFECTIONS

摘要

This utility model relates to an antibacterial cream composition to help skin infections caused by Staphylococcus aureus. The active ingredients are karimbuaya (Euphorbia neriifolia), pako (Diplazium esculentum), and mayana (Coleus blumei) aqueous extracts. Before the preparation of the cream, the plants undergone phytochemical screening. The results revealed that the each consists of phytochemical constituents that effectively kills Staphylococcus aureus. Physicochemical, acute dermal toxicity and antibacterial tests of the cream showed positive results and high acceptance upon evaluation.