Aromatic compound and use thereof in the treatment of disorders associated with bone metabolism

摘要

A compound of the formula (I) or a pharmacologically acceptable salt: ** Formula ** wherein each substituent is as defined below R1: cyano group, C1-6 alkylcarbonyl group, C1-6 alkylcarbonylamino group, halogen C1 alkyl group -6, C2-6 alkenyl group, C2-6 alkenyl halogen group, carbamoyl group, or C1-6 hydroxy group alkyl R2: C1-6 alkoxy group, carbamoyl group, C1-6 alkylaminocarbonyl group, or C1-6 alkylcarbonyl group R3 hydrogen atom, or halogen atom S, T and U: when any one of S, T and U is = N-, others are = CH- (= C- when R3 is substituted); or each of S, T and U is = CH- (= C- when R3 is substituted) W: -NH-, -O- or -SX: -saturated hepterocycle- or -O- (CH2) n-, and n is 2 Y: single bond, or -OZ: hydrogen atom, saturated heterocyclic group optionally substituted by any group selected from the group of substituents α, or C 1-6 alkyl group optionally substituted by any group selected from the group of substituents α group of substituents α: saturated heterocyclic group, hydroxy group C 1-6 alkyl, aminosulfonylamino group, carboxy group, hydroxy group, C 1-6 alkoxy group, C 1-6 alkyl group.