Novel microbial producers of succinic acid and purification of succinic acid

摘要

A process for the fermentative production of succinic acid or a salt or derivative thereof, a process comprising the steps of: a. incubating a bacterial strain in a medium containing at least glycerol as a source of assimilable carbon and culturing said strain under conditions that favor the formation of the desired succinic acid; and b. obtaining said succinic acid or salt or derivative thereof from the medium, wherein said bacterial strain is a bacterial strain of the Pasteurellaceae family, capable of using glycerol as a carbon source for the fermentative production of succinic acid, wherein said strain contains a mutated gene encoding a pyruvate enzyme lyase format with decreased or undetectable activity, the process of which includes fermentation production of succinic acid and control of pH with NH4HCO3, (NH4) 2CO3, NaOH, Na2CO3, NaHCO3, KOH, K2CO3 , KHCO3, Mg (OH) 2, MgH (CO3) 2, Ca (OH) 2, CaCO3, Ca (HCO3) 2, CaO, CH6N2O2, C2H7N and / or mixtures thereof.