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BARD1 isoforms in lung and colorectal cancer and their use
BARD1 isoforms in lung and colorectal cancer and their use
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机译:BARD1亚型在肺癌和大肠癌中的应用
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摘要
Method for detecting the presence of a lung cancer-specific BARD1 isoform in a biological sample obtained from a subject comprising the step of detecting, in said sample, at least one of the BARD1-specific isoforms of lung cancer selected from the group comprising the π isoform comprising SEQ ID NO: 1, and a sequence with at least 95% homology to SEQ ID NO: 1, where the presence of said isoforms of Lung cancer specific BARD1 in a sample from said subject is an indication that said subject has lung cancer, is at increased risk of lung cancer and / or has a risk of recurrence after treatment for lung cancer .
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机译:用于检测从受试者获得的生物学样品中肺癌特异性BARD1同工型的存在的方法,该方法包括以下步骤:在所述样品中检测选自包括π的组的肺癌的至少一种BARD1特异性同工型。包含SEQ ID NO:1的同工型,以及与SEQ ID NO:1具有至少95%同源性的序列,其中来自所述受试者的样品中肺癌特异性BARD1的所述同工型的存在表明该受试者患有肺癌,患肺癌的风险增加和/或在接受肺癌治疗后有复发的风险。
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