CO-fumarate release molecule hybrids, their use in the treatment of inflammatory or cardiovascular diseases and their preparation procedure

摘要

The present invention relates to hybrid fumarate-CO-releasing molecules capable of increasing heme oxygenase-1 (HO-1) activity and HO-1 protein expression and simultaneously releasing CO, their synthesis and their use in therapeutic applications, in particular their use in the treatment of inflammatory or cardiovascular diseases.