Disclosed herein are methods for forecasting response to lupus nephritis (LN)therapy inindividual diagnosed with childhood-onset SLE (cSLE). The methods may includethe step ofdetecting each protein in a protein set in a sample obtained from anindividual in needthereof. The protein set may include ceruloplasmin, kidney injury molecule 1(KIM-1),monocyte chemotactic protein 1 (MCP-1), adiponectin, hemopexin, and NGAL.
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