PD-1 TARGETED HETERODIMERIC FUSION PROTEINS CONTAINING IL-15/IL-15RA FC-FUSION PROTEINS AND PD-1 ANTIGEN BINDING DOMAINS AND USES THEREOF

摘要

The present invention is directed to novel PD-1-targeted IL-l5/Ra-Fc fusion proteins comprising an IL-l5/IL-l5Ra Fc-fusion protein and a PD-l antigen binding domain. The PD-1-targeted IL-l5/Ra-Fc fusion proteins can be administered to a patient to treat cancer.