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COMPOSITION FOR USE IN THE TREATMENT OF EXTRAOESOPHAGEAL GASTRIC REFLUX SYMPTOMS

机译:用于治疗食管外胃食管反流症状的组合物

摘要

The present invention relates to a liquid mixture or solid mixture, in powder or granules, comprising or, alternatively, consisting of alginic acid and hyaluronic acid, or a salt thereof, for use in the treatment, in particular in the curative treatment, of extraoesophageal symptoms or disorders caused or provoked by gastroesophageal reflux (GERD) or by a partial reflux of gastric contents, such as, for example, the partial upflow of pepsin, hydrochloric acid, gastric juices or acidic gastric vapours from the stomach and wherein said disorders or symptoms manifest themselves in an extraoesophageal region. The present invention further relates to a liquid composition or solid composition, in powder or granules, which comprises said liquid or solid mixture comprising or, alternatively, consisting of alginic acid and hyaluronic acid, or a salt thereof, and optionally pharmaceutical or food grade additives or excipients, for use in the treatment, in particular in the curative treatment, of extraoesophageal disorders or symptoms that manifest themselves in the extraoesophageal region represented by the eye or eyeball and/or periocular region in patients affected by gastroesophageal reflux (GERD) or by a partial reflux of gastric contents, such as, for example, the partial upflow of pepsin, hydrochloric acid, gastric juices or acidic gastric vapours from the stomach.
机译:本发明涉及粉末状或颗粒状的液体混合物或固体混合物,其包含或替代地由藻酸和透明质酸或其盐组成,用于治疗食道外食道,特别是用于治愈性食道道由胃食管反流(GERD)或胃内容物的部分回流引起或引起的症状或失调,例如胃蛋白酶,胃酸,胃液或酸性胃蒸气从胃中部分流出,其中症状表现在食管外区域。本发明进一步涉及粉末或颗粒形式的液体组合物或固体组合物,其包含所述液体或固体混合物,所述液体或固体混合物包含或可选地由藻酸和透明质酸或其盐以及任选的药物或食品级添加剂组成。一种或多种赋形剂,用于治疗(尤其是治疗性治疗)食管外疾病或症状,这些疾病或症状表现在受胃食管反流(GERD)或受胃食管反流影响的患者的眼,眼球和/或眼周区域代表的食管外区域胃内容物的部分回流,例如胃中胃蛋白酶,盐酸,胃液或酸性胃蒸气的部分上流。

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