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TARGET MEDIATED IN SITU SIGNAL AMPLIFICATION WITH DUAL INTERACTING HAIRPIN PROBES

机译：具有双交互发夹问题的原位 信号放大目标

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摘要

The present invention relates to the detection of nucleic acids sequences in situ using hybridization probes and generation of amplified hybridization signals, wherein background signal is reduced and sensitivity is increased. 展开▼

机译：本发明涉及使用杂交探针对核酸序列的检测和扩增的杂交信号的产生，其中降低了背景信号并且提高了灵敏度。 展开▼

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公开/公告号WO2018217905A1

专利类型

公开/公告日2018-11-29

原文格式PDF

申请/专利权人 RUTGERS THE STATE UNIVERSITY OF NEW JERSEY;
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申请/专利号WO2018US34150

发明设计人 TYAGI SANJAY;MARRAS SALVATORE A. E.;
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申请日2018-05-23

分类号C07H21/04;C12Q1/68;C12Q1/6813;C12Q1/682;C12Q1/6827;C12Q1/6841;

国家 WO

入库时间 2022-08-21 11:57:56

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