首页> 外国专利> SAFE DIRECT CURRENT STIMULATOR DESIGN FOR REDUCED POWER AND INCREASED RELIABILITY

SAFE DIRECT CURRENT STIMULATOR DESIGN FOR REDUCED POWER AND INCREASED RELIABILITY

机译:安全的直接电流激励器设计,可降低功率并提高可靠性

摘要

Current state of the art neural prosthetics, such as cochlear implants, spinal cord stimulators, and deep brain stimulators use implantable pulse generators (IPGs) to excite neural activity. Inhibition of neural firing is typically indirect and requires excitation of neurons that then have inhibitory projections downstream. The present invention is directed to a safe direct current stimulator (SDCS) technology that is designed to convert electronic pulses delivered to electrodes embedded within an implantable device to ionic direct current (iDC) at the output of the device. iDC from the device can then control neural extracellular potential with the intent of being able to not only excite, but also inhibit and sensitize neurons, thereby greatly expanding the possible applications of neuromodulation therapies and neural interface mechanisms. The device of the present invention is designed to reduce power consumption by a factor of 12 and to improve its reliability by a factor of 8.
机译:当前最先进的神经假体,例如耳蜗植入物,脊髓刺激器和深部脑刺激器,使用植入式脉冲发生器(IPG)来激发神经活动。抑制神经放电通常是间接的,需要激发神经元,然后刺激下游。本发明涉及一种安全的直流电刺激器(SDCS)技术,该技术被设计为将传递到嵌入在可植入装置内的电极的电子脉冲转换为装置输出处的离子直流电(iDC)。然后,来自设备的iDC可以控制神经细胞外电位,不仅能够激发神经元,而且还可以抑制和敏化神经元,从而极大地扩展了神经调节疗法和神经接口机制的可能应用。本发明的设备被设计为将功耗降低12倍,并将其可靠性提高8倍。

著录项

  • 公开/公告号WO2019010481A1

    专利类型

  • 公开/公告日2019-01-10

    原文格式PDF

  • 申请/专利权人 THE JOHNS HOPKINS UNIVERSITY;

    申请/专利号WO2018US41246

  • 发明设计人 FRIDMAN GENE YEVGENY;

    申请日2018-07-09

  • 分类号A61N1/04;A61N1/36;A61N1/20;

  • 国家 WO

  • 入库时间 2022-08-21 11:57:22

相似文献

  • 专利
  • 外文文献
  • 中文文献
获取专利

客服邮箱:kefu@zhangqiaokeyan.com

京公网安备:11010802029741号 ICP备案号:京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有
  • 客服微信

  • 服务号