Tadalafil free base-containing film dosage form containing polyethylene glycol-based polymer and/or vinyl pyrrolidone-based polymer as dispersion stabilizer

摘要

The present invention relates to a film preparation for oral administration, containing tadalafil free base, and a preparation method therefor. By adding a polyethylene glycol-based polymer and/or a vinyl pyrrolidone-based polymer as a dispersion stabilizer, it is possible to: maximize the dispersion stability of tadalafil free base in a film by using a small amount without inducing a specific odor or taste which can occur when using other dispersion stabilizers known in the relevant art; provide a film having an extremely low rate of tadalafil free base particle reaggregation; and remarkably reduce the amount of bubbles during a preparation process.