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MANUFACTURING METHOD OF ORAL DOSAGE FORM CONTAINING BERBERINE, ORAL DOSAGE FORM CONTAINING BERBERINE AND USE THEREOF
MANUFACTURING METHOD OF ORAL DOSAGE FORM CONTAINING BERBERINE, ORAL DOSAGE FORM CONTAINING BERBERINE AND USE THEREOF
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机译:含有小BER碱的口服剂型的制备方法,含有小BER碱的口服剂型及其用途
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Title: Manufacturing method of oral dosage form containing berberine, oral dosage form containing berberine and use thereof 5 The present invention relates to a manufacturing method of oral dosage form containing berberine, which contains steps of homogenization of berberine with at least one glidant to obtain a homogenous mixture, homogenization of the mixture with at least one filler; homogenization of the resulting mixture with at least one lubricant, followed by dry granulation and sieving, and further 10 homogenization of the granulated mixture with at least one disintegrant, followed by homogenization of the mixture with at least one lubricant, and preparation of oral dosage form selected from tablets, pills, orally disintegrating tablets, using the final homogenized mixture. The invention further relates to the oral dosage form containing berberine and to the use thereof.
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