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Surgically-friendly tissue papers from organ-specific decellularized extracellular matrices

机译:器官特异性脱细胞细胞外基质对外科友好的薄纸

摘要

Provided herein are inks including decellularized extracellular matrix (dECM) particles and scaffolds made from the inks. Also provided are methods of making the scaffolds and applications for the scaffolds. In an embodiment, a porous scaffold comprises dECM particles and an elastomer, wherein the scaffold is planar having a thickness of about 100 μm or greater, the scaffold comprises irregularly shaped pores having a random orientation and distribution throughout the scaffold, and the scaffold is free of crosslinking between the molecular components of the scaffold.
机译:本文提供了包括脱细胞的细胞外基质(dECM)颗粒和由该油墨制成的支架的油墨。还提供了制备支架的方法和用于支架的用途。在一个实施方案中,多孔支架包含dECM颗粒和弹性体,其中所述支架是平面的,具有约100μm或更大的厚度,所述支架包括不规则形状的孔,所述不规则形状的孔在整个支架上具有随机的取向和分布,并且所述支架是自由的。支架的分子组分之间的交联。

著录项

  • 公开/公告号AU2017362417A1

    专利类型

  • 公开/公告日2019-06-06

    原文格式PDF

  • 申请/专利权人 NORTHWESTERN UNIVERSITY;

    申请/专利号AU20170362417

  • 发明设计人 JAKUS ADAM E.;SHAH RAMILLE N.;

    申请日2017-11-17

  • 分类号A61L31/06;A61F2;A61L31/14;

  • 国家 AU

  • 入库时间 2022-08-21 11:56:14

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