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Inhibitors of SOX18 protein activity for treating angiogenesis- and/or lymphangiogenesis-related diseases

机译:用于治疗血管生成和/或淋巴管生成相关疾病的SOX18蛋白活性抑制剂

摘要

Disclosed are compounds of a formula provided herein that show efficacy in the inhibition of SOX18 protein activity, and in particular with respect to the ability of SOX18 to bind DNA and/or particular protein partners. Further, methods of treating angiogenesis- and/or lymphangiogenesis-related diseases, disorders or conditions, such as cancer metastasis and vascular cancers, are provided herein.
机译:公开了本文提供的式的化合物,其显示出抑制SOX18蛋白活性的功效,特别是关于SOX18结合DNA和/或特定蛋白伴侣的能力。此外,本文提供了治疗与血管生成和/或淋巴血管生成相关的疾病,病症或病状例如癌症转移和血管癌的方法。

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