Functionalized magnetic nanoparticles and use in imaging amyloid deposits and neurofibrillary tangles

摘要

#$%^&*AU2019203038A120190523.pdf#####ABSTRACT OF THE DIsCLOSURE The present disclosure provides functionalized magnetic nanoparticles (MNPs) comprising a functional group that binds to p-amyloid deposits and/or neurofibrillary tangles. The present disclosure provides compositions comprising the functionalized MNPs, and methods of using the functionalized MNPs in imaging -amyloid deposits and neurofibrillary tangles.