Statistical artificial intelligence for advanced deep learning and probabilistic programing in the biosciences is provided. In various embodiments, biological data of a population is read. The biological data include molecular features of the population. A plurality of features of the population is extracted from the biological data. The plurality of features is provided to a first trained classifier to determine a subset of the plurality of features distinguishing the population. A plurality of genes associated with the subset of the plurality of features is determined. The plurality of genes is provided to a second trained classifier to determine a subset of the plurality of genes distinguishing the population. A dependence model is applied to the subset of the plurality of genes to determine one or more drug target.
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