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HEAT-INACTIVATED VACCINIA VIRUS AS A VACCINE IMMUNE ADJUVANT
HEAT-INACTIVATED VACCINIA VIRUS AS A VACCINE IMMUNE ADJUVANT
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机译:热灭活的疫苗病毒作为疫苗免疫佐剂
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摘要
The technology of the present disclosure relates to the use of Heat-inactivated modified vaccinia Ankara (MVA) virus (Heat-iMVA) or Heat-inactivated vaccinia virus as a vaccine immune adjuvant. In particular, the present technology relates to the use of Heat-iMVA as a vaccine adjuvant for tumor antigens in cancer vaccines alone or in combination with immune checkpoint blockade (ICB) antibodies for use as a cancer immunotherapeutic.
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