USE OF A P2X₇ RECEPTOR ANTAGONIST TO TREAT AN INFLAMMATORY DISEASE OR DISORDER

摘要

The present disclosure relates to a method for the treatment, amelioration, and/or prevention of P2X7 receptor-mediated diseases or disorders in a subject in need thereof. Such disorders include liver fibrosis, nonalcoholic steatohepatitis, cirrhosis and hepatocellular carcinoma. The method includes the administration of a P2X7 receptor antagonist to the subject. Also described are compositions for treatment as well as dosing regimens.