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METHOD FOR AIDING DETECTION OF ALZHEIMER'S DISEASE

机译:一种辅助检测老年痴呆症的方法

摘要

Disclosed is a method for aiding the detection of Alzheimer's disease that aids highly accurate detection of Alzheimer's disease. The method for aiding the detection of Alzheimer's disease uses, as an indicator, the amount present in a test sample isolated from a living subject of at least one molecule from an miRNA, or the like, for which the base sequence is identified by any sequence from among SEQ ID NOs: 1–85. When the amount of at least one miRNA, or the like, for which the base sequence is identified by any sequence from among SEQ ID NOs: 1–22 and 66–71 is higher than that of a healthy subject, or when the amount of at least one miRNA, or the like, for which the base sequence is identified by any sequence from among SEQ ID NOs: 23–65 and 72–85 is lower than that of a healthy subject, there is a high possibility of developing Alzheimer's disease.
机译:公开了一种辅助阿尔茨海默氏病检测的方法,该方法有助于高度准确地检测阿尔茨海默氏病。辅助检测阿尔茨海默氏病的方法使用从生活对象分离的测试样品中存在的至少一种来自miRNA等分子的至少一个分子的量作为指标,该序列的碱基序列可通过任何序列来鉴定。在SEQ ID NO:1-85中。当至少一个miRNA等(其碱基序列被SEQ ID NO:1-22和66-71中的任意序列识别)的数量高于健康受试者的数量时,或至少一种miRNA等,其碱基序列由SEQ ID NOs:23-65和72-85中的任何序列所鉴定,比健康受试者的miRNA更低,因此很可能发生阿尔茨海默氏病。

著录项

  • 公开/公告号WO2019117306A1

    专利类型

  • 公开/公告日2019-06-20

    原文格式PDF

  • 申请/专利权人 HIROSHIMA UNIVERSITY;

    申请/专利号WO2018JP46198

  • 发明设计人 TAHARA HIDETOSHI;

    申请日2018-12-14

  • 分类号C12N15/113;C12Q1/6809;

  • 国家 WO

  • 入库时间 2022-08-21 11:54:20

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