COMBINING PH AND METABOLIC ACTIVITY IMAGING FOR RESPONSE ASSESSMENT IN IMMUNE THERAPY

摘要

A computerized system for monitoring cancer therapy and a related method. The system comprises an input port (IN) for receiving two or more input images acquired of a subject, the two or more input images capable of recording metabolic activity and extracellular pH level. An evaluator (EVAL) of the system is configured to assess, based on the input images, i) a change over time in metabolic activity and ii) a change over time in extracellular pH level. The evaluator (EVAL) is further configured to establish, based on the assessment, an indication on whether or not there is a response to a cancer therapy in relation to a lesion of the subject or on whether the assessment is inconclusive. The indication is output through an output interface (OUT).