NOVEL IL-4-/IL-13-DERIVED PEPTIDE COMPOUNDS FOR THE TREATMENT OR PREVENTION OF NEURODEGENERATIVE OR NEUROINFLAMMATORY DISEASES

摘要

The present invention relates to a compound consisting of one or more peptides comprising the structure in the following order: A - L1 - B - L2 - C wherein A corresponds to a first amino acid sequence that is derived from A or C alpha helical region of human or animal IL-4 or IL-13, B corresponds to a second amino acid sequence that is derived from A or C alpha helical region of human or animal IL-4 or IL-13, C corresponds to a third amino acid sequence that is derived from D or B alpha helical region of human or animal IL-4, or D alpha helical region of human or animal IL-13. L1 and L2 correspond to one or more linking amino acids, wherein said compound is capable of stimulating neuronal axon outgrowth.