SYSTEM AND METHOD USING LOCAL UNIQUE FEATURES TO INTERPRET TRANSCRIPT EXPRESSION LEVELS FOR RNA SEQUENCING DATA

摘要

A method (100) for characterizing gene transcript expression levels, comprising: (i) extracting (110) one or more unique features from each of a plurality of gene transcripts; (ii) storing (120) the extracted unique features in a unique feature database; (iii) receiving (130) a plurality of sequences sequenced from gene transcripts, wherein at least some of the sequences comprise one or more of the extracted unique features; (iv) comparing (140), by a processor, the plurality of sequences to the extracted unique features stored in the unique feature database; (v) identifying (150), based on a match between a sequence and an extracted unique feature, a gene transcript and/or gene from which the sequence was generated; and (vi) compiling (160) information about gene transcript expression levels based on said identified gene transcripts.