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APPARATUS AND METHOD FOR MEASURING DEGRADATION KINETICS OF A BIOMATERIAL IN AQUEOUS SOLUTION BELOW THE NORMAL FREEZING TEMPERATURE
APPARATUS AND METHOD FOR MEASURING DEGRADATION KINETICS OF A BIOMATERIAL IN AQUEOUS SOLUTION BELOW THE NORMAL FREEZING TEMPERATURE
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机译:在低于正常冷冻温度的水溶液中测量生物材料降解动力学的装置和方法
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摘要
This present disclosure describes an apparatus and a method for measuring degradation kinetics of a biomaterial in aqueous solution below the normal freezing temperature. Further includes new systems comprising high-pressure containers with nucleating-locks, a temperature-control holder for the high-pressure containers, a holder for the nucleating-locks and an insulated low-temperature gradient chamber. A method is described comprising several steps such as filling of the high-pressure container with the biomaterial solution to be slightly below freezing temperature, closing of the container with a nucleating-lock, which is below freezing temperature, allowing the container to reach the reaction temperature, removing the container at selected time and bringing it to above freezing temperature and opening the container to recover the biomaterial solution.
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