CLINICAL INTERPRETATION OF GENOMIC AND TRANSCRIPTOMIC DATA AT THE POINT OF CARE FOR PRECISION CANCER MEDICINE

摘要

Feature-based clinical interpretation of whole exome and transcriptome data for precision cancer medicine is provided. In various embodiments, genomic data of a subject is received. The genomic data comprises somatic mutations. A plurality of features is determined from the genomic data of the subject. A similarity metric is determined between the plurality of features and each of a plurality of reference genomes. One or more potentially actionable feature is determined from the similarity.