BIOREACTOR WITH FREEZE-THAW CAPABILITIES TO ENHANCE PRODUCT RECOVERY AND RELATED METHODS

摘要

An apparatus is provided for bioprocessing, such as for culturing cells. The apparatus includes a bioreactor with a chamber having cells and a chamber for temperature regulation of the cells. In some embodiments, a freezer is connected to the bioreactor for freezing the cells in the chamber, and a heater may also be provided for actively thawing the cells. Related methods are also disclosed.