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The crystalline form of (R) -4- (5- (cyclopropylethynyl) isoxazol-3-yl) -N-hydroxy-2-methyl-2- (methylsulfonyl) butanamide as an antibacterial agent
The crystalline form of (R) -4- (5- (cyclopropylethynyl) isoxazol-3-yl) -N-hydroxy-2-methyl-2- (methylsulfonyl) butanamide as an antibacterial agent
The present invention relates to (R) -4- (5- (cyclopropylethynyl) isoxazol-3-yl) -N-hydroxy-2-methyl-2- (methylsulfonyl) To a crystalline form of a compound of formula (A). The compounds and compositions thereof are useful for treating bacterial infections and gram-negative bacterial infections, particularly multidrug-resistant strains. The crystalline form is prepared by dissolving the amorphous form of the compound in a halogenated organic solvent (e.g. dichloromethane) and precipitating in a crystalline form with a hydrocarbon solvent (e. G. Heptane).
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