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Diagnostic strategy and tool for successful weaning from renal replacement therapy after acute kidney injury

机译:急性肾损伤后成功撤离肾脏替代疗法的诊断策略和工具

摘要

The present invention is in a field of treatment of renal diseases. More specifically, the present invention, as a method for determining when to stop renal replacement therapy, relates to a method for determining the timing of discontinuation of renal replacement therapy due to acute kidney injury and a diagnostic kit for determining the timing of discontinuation thereof, wherein, in particular, it is possible to successfully predict and determine when to stop the renal replacement therapy when renal replacement therapy such as hemodialysis is performed due to acute kidney injury. The method for determining the timing of discontinuation of renal replacement therapy comprises the steps of: providing a biological fluid sample obtained from a patient undergoing the renal replacement therapy with acute kidney injury; measuring a cystatin C value in the fluid sample provided; and determining the timing of discontinuation of the renal replacement therapy based on the measured cystatin C value.
机译:本发明属于肾脏疾病的治疗领域。更具体地,作为确定何时停止肾脏替代治疗的方法,本发明涉及一种确定由于急性肾损伤导致的肾脏替代治疗的中止时间的方法以及用于确定其停止时间的诊断试剂盒,其中,特别地,当由于急性肾损伤而进行诸如血液透析的肾脏替代疗法时,可以成功地预测并确定何时停止肾脏替代疗法。用于确定中止肾脏替代疗法的时机的方法包括以下步骤:向得自经历肾脏替代疗法的患者的急性肾损伤的生物流体样品提供;测量所提供的液体样品中的胱抑素C值;并根据测得的胱抑素C值确定停止肾脏替代治疗的时机。

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