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miR-205 Use of miR-205 for diagnosis of hearing loss

机译:miR-205使用miR-205诊断听力损失

摘要

The present invention relates to miR-205 for diagnosis of hearing loss. More specifically, the present invention has selected miR-205 as microRNA for early diagnosis of hearing loss in mice with ototoxic hearing loss, and has confirmed that the expression of microRNA-205, from an early stage of hearing loss, continuously increases in stria vascularis and modiolus tissue samples of the ear and serum samples of the mice with ototoxic hearing loss, compared to normal mice of a control group. Thus, miR-205 of the present invention can be used as a biomarker for early diagnosis of hearing loss.
机译:本发明涉及用于听力丧失诊断的miR-205。更具体地,本发明选择miR-205作为用于耳毒性听力损失的小鼠的听力损失的早期诊断的microRNA,并且已经证实,从听力丧失的早期开始,microRNA-205的表达在血管纹中不断增加。与对照组的正常小鼠相比,耳毒性和耳毒性的小鼠的耳蜗和粪便组织样本以及血清样本。因此,本发明的miR-205可用作早期诊断听力损失的生物标记。

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