Injectable compositions comprising fibroblasts, which can be used for the treatment of heart diseases, and methods of producing fibroblasts for therapeutic use

摘要

The present invention aims to provide a method which is useful for achieving long-term and fundamental healing of necrotic heart tissue regions and which has not yet been established to enable recovery of the functionality of the heart. The present invention provides an injectable composition for the treatment of heart disease, the composition comprising fibroblasts, wherein the fibroblasts comprise CD106-positive fibroblasts, preferably CD90-positive fibroblasts.