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Colicin D Use of Colicin D fragment for treating cancer

机译:Colicin D Colicin D片段在治疗癌症中的用途

摘要

The present invention relates to a use of colicin D fragment for treating cancer. A composition according to the present invention contains polynucleotides encoding some fragments in colicin D protein derived from colon bacillus as an active component, wherein the fragments selectively kill only cancer cells, thereby exhibiting significant anticancer effects. That is, the present invention solves the toxicity problem for general cells, which has been pointed out as a limitation of an existing gene therapeutic agent, and can be used as a core technology in the field of gene therapy for cancer treatment.
机译:大肠菌素D片段在治疗癌症中的用途本发明涉及大肠菌素D片段在治疗癌症中的用途。根据本发明的组合物包含编码源自结肠杆菌的大肠菌素D蛋白中的一些片段的多核苷酸作为活性成分,其中所述片段仅选择性地杀死癌细胞,从而表现出显着的抗癌作用。即,本发明解决了对普通细胞的毒性问题,该毒性问题已被指出为现有基因治疗剂的局限性,并且可以用作癌症治疗的基因治疗领域的核心技术。

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