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Novel transdermal protein composition for preventing hair loss and promoting hair growth and the use thereof

机译:用于预防脱发和促进头发生长的新型透皮蛋白质组合物及其用途

摘要

The present invention relates to a skin permeable protein mixed composition having hair loss prevention and hair growth promotion effects, and a use thereof. A composition comprising one or more selected from a basic fibroblast growth factor (FGF2) recombinant protein, a recombinant protein combined with a PEP-1 peptide, a recombinant protein in which a fibroblast growth factor 9 (FGF9) and a PEP-1 peptide are bound, a recombinant protein in which a vascular endothelial growth factor (VEGF) and a PEP-1 peptide are bound, and a recombinant protein in which thioredoxin 1 (TRX1) and a PEP-1 peptide are bound are excellently permeated into cells and skin, and exhibit excellent hair growth promoting effects. By using the effects, the present invention can be effectively used as a cosmetic composition for preventing hair loss and a pharmaceutical composition comprising the recombinant protein composition as an active ingredient.
机译:本发明涉及具有防止脱发和促进毛发生长的效果的皮肤渗透性蛋白质混合组合物及其用途。一种组合物,其包含选自碱性成纤维细胞生长因子(FGF2)重组蛋白,与PEP-1肽结合的重组蛋白,其中成纤维细胞生长因子9(FGF9)和PEP-1肽为重组蛋白的一种或多种。结合后,结合有血管内皮生长因子(VEGF)和PEP-1肽的重组蛋白,以及结合了硫氧还蛋白1(TRX1)和PEP-1肽的重组蛋白可以很好地渗透到细胞和皮肤中,并具有出色的促进头发生长的效果。通过使用该效果,本发明可以有效地用作防止脱发的化妆品组合物和包含重组蛋白组合物作为活性成分的药物组合物。

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