EGFR- Novel Biomarkers for Predicting Susceptibility to EGFR-Targeting Agent and Uses Thereof

摘要

The present invention relates to a novel biomarker for predicting susceptibility to an EGFR-target agent and a use thereof. More particularly, the present invention relates to an EGFR (Epidermal Growth Factor Receptor) - biomarkers for predicting susceptibility to target products; Gene expression level of the biomarker; Or a composition for predicting susceptibility to an EGFR-target agent, comprising an agent for measuring the expression or activity level of a protein of said gene; A composition for promoting susceptibility to an EGFR-target agent comprising the expression of the gene or the expression or activity inhibitor of the protein of the gene as an active ingredient; A kit for predicting susceptibility to an EGFR-target formulation comprising said composition; And methods for predicting susceptibility to EGFR-targeted agents. According to the present invention, the present invention is excellent in predicting the susceptibility to an EGFR-target preparation in colorectal cancer, so that the present invention can be usefully used for the treatment of colon cancer.