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Peptides having cytoprotective effects against environmental pollutants and use thereof
Peptides having cytoprotective effects against environmental pollutants and use thereof
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机译:具有针对环境污染物的细胞保护作用的肽及其用途
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摘要
The present invention relates to a peptide having cytoprotective effect against environmental pollutants and a use thereof, and relates to a peptide having an amino acid sequence of SEQ ID NO: 1, 2 or 3, Tetrachlorodibenzodioxin (hereinafter referred to as TCDD) to prevent penetration into the skin, and to prevent the AhR activation mechanism by polycyclic aromatic hydrocarbons contained in TCDD and fine dusts , The cytoprotective effect of this direct environmental contaminant is different from the existing methods of indirectly preventing contact with substances or reducing toxicity through barrier enhancement.
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机译:本发明涉及对环境污染物具有细胞保护作用的肽及其用途,并且涉及具有SEQ ID NO:1、2或3的氨基酸序列的四氯二苯并二恶英(下文称为TCDD)以防止渗透的肽。进入皮肤,并通过TCDD和细粉尘中的多环芳烃防止AhR激活机制,这种直接环境污染物的细胞保护作用与现有的间接预防与物质接触或通过增强屏障降低毒性的方法不同。
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