BUB3 AURKB PTTG1 RAD21 DIAGNOSTIC METHODS FOR PROGNOSIS OF NON-SMALL-CELL LUNG CANCER USING BUB3 AURKB PTTG1 AND RAD21 SNPs

摘要

The present invention relates to single nucleotide polymorphisms of the BUB3, AURKB, PTTG1 and RAD21 genes for prediction of the prognosis of non-small cell lung cancer (NSCLC). More specifically, the BUB3 gene uses SNP of rs7897156, Methods for diagnosing and predicting the prognosis of early stage non-small cell lung cancer using the rs1059476 SNP, the rs1059476 SNP, the rs1895320 SNP, and the RAD21 gene using rs1374297 SNP And its use. The prognosis of non-small cell lung cancer survival prognosis according to the present invention can be evaluated by easily evaluating the prognosis of patients with non-small cell lung cancer and by targeting means and treatment for selection and evaluation of treatment methods, .