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Cationic cyclodextrin derivatives and drug delivery system using thereof

机译:阳离子环糊精衍生物及其使用的药物递送系统

摘要

The present invention relates to capturing drugs and syntehsizing cyclodextrin derivatives, which can be used as a drug delivery system that makes delivery to cells easy by the encapsulation of a hydrophobic substance used as a drug. In addition, the present invention provides a drug delivery method capable of generating liposomes by using the cyclodextrin derivatives and carrying a drug thereon. The present invention forms liposomes using cyclodextrins, so that a separate and conventional step for forming a liposome is not necessary, and a hydrophilic part inside the liposome can carry a hydrophilic drug, and a hydrophobic drug can be carried in a hydrophobic part corresponding to the phospholipid portion of the liposome.
机译:本发明涉及捕获药物并合成环糊精衍生物,其可以用作药物递送系统,其通过封装用作药物的疏水性物质而使向细胞的递送变得容易。另外,本发明提供了能够通过使用环糊精衍生物并在其上携带药物来产生脂质体的药物递送方法。本发明使用环糊精形成脂质体,因此不需要单独的常规步骤来形成脂质体,并且脂质体内的亲水性部分可以携带亲水性药物,而疏水性药物可以携带在与脂质体相对应的疏水性部分中。脂质体的磷脂部分。

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