Pharmaceutical composition for preventing or treating of ischemic reperfusion injury comprising bile acids

摘要

The present invention relates to a composition for preventing, treating or ameliorating ischemic reperfusion injury comprising bile acid. According to the present invention, the bile acid has an excellent effect of increasing the nuclear level of beta -catenin and inhibiting the opening of mPTP (mitochondria permeable transition pore) and improving tissue damage and reducing infarct size in an ischemic reperfusion injury animal model, Can be usefully used for the prevention, treatment or improvement of reperfusion injury.