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IgM Monoclonal IgM type antibody specific binding odontoblasts surface and uses thereof

机译:IgM单克隆IgM型抗体特异性结合成牙本质细胞表面及其用途

摘要

The present invention relates to an IgM type monoclonal antibody that specifically binds to the surface of differentiated odontoblasts differentiated from pulp stem cells, and to a composition and method for screening odontoblast differentiation, odontoblast separation, and odontoblast differentiation promoting substance using the same. When using an IgM monoclonal antibody that specifically binds to the odontoblast of the present invention, it is possible to effectively isolate and purify an oblast that can be useful for tissue regeneration and differentiation. It can also be usefully used for the screening of substances that effectively promote differentiation into odontoblasts.
机译:本发明涉及与从牙髓干细胞分化的分化成牙本质细胞表面特异性结合的IgM型单克隆抗体,并涉及用于筛选成牙本质细胞分化,成牙本质细胞分离和成牙本质细胞分化促进物质的组合物和方法。当使用与本发明的成牙本质细胞特异性结合的IgM单克隆抗体时,可以有效地分离和纯化可用于组织再生和分化的成纤维细胞。它也可用于筛选有效促进分化为成牙本质细胞的物质。

著录项

  • 公开/公告号KR102008960B1

    专利类型

  • 公开/公告日2019-08-08

    原文格式PDF

  • 申请/专利权人 단국대학교 천안캠퍼스 산학협력단;

    申请/专利号KR20170164410

  • 发明设计人 장영주;

    申请日2017-12-01

  • 分类号C07K16/28;C12N5/077;C12N5/12;G01N33/569;

  • 国家 KR

  • 入库时间 2022-08-21 11:48:03

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