PHARMACEUTICAL COMPOSITION COMPRISING THE SEED EXTRACT OF LITCHI AS AN EFFECTIVE COMPONENT FOR PREVENTION OR TREATMENT OF THROMBOSIS AND HEALTH FUNCTIONAL FOOD COMPRISING THE SAME

摘要

The present invention relates to an antithrombotic composition containing seed extract of Litchi chinensis Sonn., A kind of tropical fruit, as an active ingredient. The present invention relates to a pharmaceutical composition and health functional food for preventing or treating / improving thrombosis through inhibiting blood coagulation, which contains a rich seed extract prepared by extracting the excluding seeds and extracting them with ethanol as an active ingredient. Rich seed extract as an active ingredient of the pharmaceutical composition for the prevention or treatment of thrombosis of the present invention and the health functional food, because it uses the extract of the seed discarded after the edible fruit of edible fruit can contribute to the reuse of insoluble resources and environmental conservation, As demonstrated by the examples herein, it exhibits strong antithrombotic activity by inhibition of enzymes related to thrombus production and inhibition of blood coagulation factors, and shows no hemolytic activity against human erythrocytes, and is excellent in thermal stability. , no loss of blood coagulation factor inhibitory effect in acidic conditions and plasma of pH 2, it is expected to be used for the prevention and treatment of thrombosis such as ischemic stroke and hemorrhagic stroke through improved blood circulation, the active ingredient extract It is processed into various forms such as powder, pill and tablet so that it can be taken at all times It is a very useful invention for the pharmaceutical industry and food industry because it has an excellent effect that can be prepared in one form.