CISH CISH marker predictive of responsiveness to immunotherapy in a patient with gastrointestinal cancer and use thereof

摘要

The present invention relates to a biomarker for predicting immunotherapy reactivity of a gastrointestinal cancer patient and its use, and more particularly, comprising a cytokine inducible SH2 containing protein (CISH) gene or a protein encoded by the gene. The present invention relates to a marker composition for predicting reactivity, a composition for predicting immunotherapy reactivity, and a method for providing information for predicting immunotherapy reactivity. The biomarker according to the present invention is classified into immune response grades, prognostic prediction, and immunotherapy for RNA extracted from cancer-derived tissues that can be easily obtained and stored for a long time, such as formalin fixed paraffin-embedded tissue. It can be usefully used to predict the reactivity to.