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B- Method for predicting of resistance against therapeutic agent in diffuse large B-cell lymphoma patients

机译:B-预测弥漫性大B细胞淋巴瘤患者对治疗剂耐药的方法

摘要

The present invention relates to a composition for predicting drug resistance in patients with diffuse large B-cell lymphoma and a method for predicting resistance using the same. More specifically, the present invention relates to a diffuseness comprising an agent detecting a mutation of a specific gene and / or a copy number variation of a specific gene. The present invention relates to a composition for predicting drug resistance in patients with giant B-cell lymphoma and a prediction method using the same. By predicting treatment resistance through mutation of a specific gene and / or increasing or decreasing the number of copies of a specific gene provided in the present invention, it is possible to quickly and accurately predict the drug reactivity of individual patients with diffuse large B-cell lymphoma, thereby preventing unnecessary drug treatment. It can alleviate the physical, mental and economic pain of the patient, which is very meaningful given the quality of life during the patient's treatment.
机译:本发明涉及用于预测弥漫性大B细胞淋巴瘤患者的耐药性的组合物和使用该组合物预测耐药性的方法。更具体地,本发明涉及一种扩散,其包括检测特定基因的突变和/或特定基因的拷贝数变异的试剂。本发明涉及用于预测巨细胞B细胞淋巴瘤患者的耐药性的组合物和使用该组合物的预测方法。通过通过本发明提供的特定基因的突变和/或增加或减少特定基因的拷贝数来预测治疗抗性,可以快速而准确地预测具有弥散性大B细胞的个体患者的药物反应性淋巴瘤,从而防止不必要的药物治疗。它可以减轻患者的身体,精神和经济痛苦,考虑到患者治疗期间的生活质量,这非常有意义。

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